Directions: In the following sentence, four words given in bold are marked as A, B, C, and D, which are possible pairs to be interchanged. Choose the pair(s) of words that need to be interchanged to make the sentence grammatically correct and meaningful. If no interchange is required, mark option 5 i.e., "No interchange required" as your answer.

Humans have always gazed at the stars, using them for spiritual (A) and navigation (B) significance, fostering dreams of space exploration (C) and technological advancement (D).