What distinguishes the regulation of the posterior pituitary from that of the anterior pituitary?

1
The hypothalamus regulates the posterior pituitary via hormonal signals through the portal system.
2
The posterior pituitary is regulated directly by neural signals from the hypothalamus.
3
The anterior pituitary is regulated by hormones from the pineal gland.
4
The posterior pituitary produces its own hormones independently of the hypothalamus.

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