How are viral vaccines like the MMR (Measles, Mumps, and Rubella) vaccine usually prepared to ensure immunogenicity while maintaining safety? A. B. Through live virus attenuation to reduce virulence but retain the ability to induce an immune response

1
By using heat-killed viruses
2
Through live virus attenuation to reduce virulence but retain the ability to induce an immune response 
3
By using purely synthetic peptides 
4
By combining bacterial and viral components

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