In each of the given number-clusters, the number on the right side of '=' (the equal to sign) is calculated by performing certain mathematical operations on the three numbers on the left of '=' (the equal to sign). All three number-clusters follow the same pattern. Select the number from among the given options that can replace the question mark (?) in the third number-cluster.
4, 3, 2 = 21
5, 6, 3 = 52
5, 8, 4 = ?
1
41
2
106
3
73
4
85