During metaphase to anaphase transition, complete removal of cohesin allows sister chromatids to separate and move to opposite poles of the spindle. Given below are a few proteins/protein complexes involved in mitotic progression.

A. Cdc20

B. APC/C

C. Separase

D. CyclinA
 
Which one of the following options represents the protein (s)/protein complexes involved in cohesin removal at the onset of anaphase during mitosis? 

1
C only
2
A only
3
A, B, and C
4
B, C, and D

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