During the initiation of DNA replication in prokaryotes, which of the following is the correct sequence of events?
1
Binding of DNA polymerase, helicase unwinding, RNA primer synthesis by primase
2
Helicase unwinding, binding of single-stranded binding proteins (SSBs), primase synthesizing RNA primers
3
RNA primer synthesis by primase, helicase unwinding, binding of DNA polymerase
4
Helicase unwinding, RNA primer synthesis by primase, ligation by DNA ligase