In immune response mechanism clonal selection is a process in which: 

1
a special type of clone cell line is identified in a cell culture 
2
the proliferation and differentiation of lymphocytes occur in response to a specific antigen 
3
cloning of a specific gene is done by inserting the same into a bacteria by recombinant DNA technology  
4
selection of an appropriate cell type is done for the purpose of cloning 

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