During physical exercise, the oxygen supply to the active muscles is increased which has been explained by the following statements:

A. PO2 declines and PCO2; rises in the active muscles

B. The temperature is increased and pH is decreased in active muscles

C. 2, 3-biphosphoglycerate is decreased in RBC 

D. Metabolites accumulating in the active muscles increase the affinity of hemoglobin to oxygen

Which one of the following is NOT correct? 

1
 A only
2
A and B 
3
B and C
4
C and D
5
Question Not Attempted

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