Match the genetic disorder (Column I) with its molecular basis (Column II)
| Column I | Column II |
| P. Sickle-cell anemia | 1. Mutation in nucleotide excision repair |
| Q. Xeroderma pigmentosum | 2. Trisomy of chromosome 21 |
| R. Tay-Sachs disease | 3. Mutation in ß-globin gene |
| S. Down Syndrome | 4. Mutation in hexosaminidase A gene |
1
P-1; Q-4; R-2; S-3
2
P-3; Q-4; R-1; S-2
3
P-3; Q-1; R-4; S-2
4
P-4; Q-1; R-3; S-2
5
Question Not Attempted