Given below is a list of regulatory RNAs (Column X) and their modes of action (Column Y).

Column X

Column Y

Regulatory RNA

Mechanism for the control of gene expression

A.

Riboswitch

i.

Base-pairing with specific mRNAs and controlling their stability and their translation.

B.

MicroRNA (miRNA)

ii.

Change their conformation when bound to small molecules, usually metabolites.

C.

Small interfering RNAs (siRNAs)

iii.

Complementary base pairing followed by RISC-mediated mRNA cleavage.

Which one of the following options represents all correct matches between Column X and Column Y?

1
A - ii, B - i, C - iii
2
A - i, B - ii, C - iii
3
A - iii, B - i, C - ii
4
A - iii, B - ii, C - i

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