Certain statements are made about protein and DNA.

A. Globular protein when treated with organic solvent gets denatured

B. Sodium dodecyl sulphate (SDS) denatures protein 

C. The Temperature of Melting (Tm) is defined as the temperature at which 100% of double-stranded DNA is changed to single-stranded DNA

D. Globular protein when treated with organic solvent does not denatured

E. The Temperature of Melting (Tm) is defined as the temperature at which 50% of double-stranded DNA is changed to single-stranded DNA.

Select the combination of all correct statements.

1
B, C and E
2
A, B and E
3
C, D and E
4
A, B and C

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