Which of the following is a correct statement about the process of DNA replication?  

1
DNA synthesis takes place mainly by DNA polymerase I in E. coli  
2
Gap filling after the removal of primer is done by DNA polymerase III  
3
SSB proteins bind to the DNA strand in which the leading strand of replicating DNA is synthesized.  
4
Direction of DNA synthesis in the lagging strand is 5’ →  3’ direction  

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