Which of the following statements accurately differentiates the Kozak sequence's role in eukaryotic translation from the Shine-Dalgarno sequence's role in prokaryotic translation?
1
Both the Kozak and Shine-Dalgarno sequences are found at the 3' end of the mRNA and play a crucial role in terminating protein synthesis.
2
The Shine-Dalgarno sequence is recognized by ribosomal RNA to initiate translation in eukaryotes, while the Kozak sequence serves a similar purpose in prokaryotes.
3
The Kozak sequence enhances the efficiency of translation initiation by orienting the ribosome at the start codon in eukaryotes, whereas the Shine-Dalgarno sequence is recognized by the small ribosomal subunit for ribosome binding near the start codon in prokaryotes.
4
The Kozak sequence and the Shine-Dalgarno sequence both operate by directly recruiting translation initiation factors that are unique to viruses.