Which of the following statements is true regarding the role of flippase, floppase, and scramblase in the movement of lipids across the phospholipid bilayer?

1
Flippase requires ATP to move lipids from the outer to the inner leaflet, while floppase and scramblase do not require ATP for their action.
2
Scramblase catalyzes the ATP-dependent transfer of phospholipids from the inner to the outer leaflet, maintaining the asymmetric distribution of lipids
3
Both flippase and floppase are ATP-dependent enzymes; however, flippase moves phospholipids from the outer to the inner leaflet, while floppase does the opposite.
4
Floppase facilitates the bidirectional movement of phospholipids across the membrane in an ATP-independent manner, contributing to the membrane's fluidity and asymmetry.

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