Regeneration is a process that rebuilds complex structures, scaled and positioned appropriately and integrated into the existing adult. Regenerative abilities vary across species, from the near-total regeneration in many plants and planarians, to the replacement of complex structures in salamanders and fish, to the very limited abilities found in mammals. This cellular replacement is generated from three cell types in Hydra .Select the correct statement on regeneration in Hydra.

1
Three cell types are all that are needed to form a hydra, and if hydra cells are separated and reaggregated, a new hydra will not form.
2
In Hydra, endodermal and ectodermal cells are Totipotent progenitor cells that divide continuously, producing more lineage-restricted epithelia.
3
Unipotent interstitial stem cell found within the ectodermal layer of Hydra.
4
Compared with the myoepithelial stem cells (endoderm and ectoderm), interstitial stem cells are paused in G2 phase of the cell cycle for a longer period and cycle at a faster rate.

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