Which one of the following statements is correct for early embryonic development in terms of differentiation?
1
The first stage of commitment is termed as specification, while the second stage is determination.
2
If a specified cell is transplanted to a region of differently specified cells, the fate of the specified cell remains unchanged.
3
A cell or tissue is said to be determined when it shows reversible fate under the influence of the surrounding cells or tissue.
4
The first stage of specification is termed as commitment when a cell develops autonomously.