With reference to Nyāya philosophy, which of the following statements is true?

1
The linga or the middle term is not the Karana or operative cause of inference.
2
The middle term may be a thing of the present but not of the past or the future.
3
The middle term can function in an inference when past or future.
4
The middle term can lead to the conclusion apart from the knowledge of Nyāya or the universal relation between it and the major term.

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