In the context of biodiversity, what do you understand by the term 'Vavilov Centre'?

1
 It refers to a geographical area where the particular group of crops (either domesticated or wild) first originated on earth.
2
It is a biogeographic region with significant levels of biodiversity that is threatened by human habitation.
3
It is a region in which the fitness of one species depends on interactions with the second species.
4
A geographical region where the primary productivity is almost zero.

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