In the sentence, certain words are in bold and numbered from A to E, which are the possible pairs to be interchanged. Choose the pair(s) of words which need to be interchanged to make the sentence grammatically correct and meaningful.

During adolescence, the prefrontal cortex becomes (A)efficiently efficient in communicating with other parts of the brain and this helps build a communication (B)system within the brain that is more (C)permitting and sophisticated, (D)distributed the different areas of the brain to process information more (E) increasingly.