In each of the questions below, a word is given, followed by four statements. From the options, choose the one that provides the combination of statements that can be joined using the given word somewhere in the sentence. 

Despite

1. Improving nutrition and managing stunting continue to be big challenges.
2. They can be addressed only with an inter-sectoral strategy.
3. There were programme commitments since 1975, such as creating Integrated Child Development Services and national coverage of the mid-day meal scheme.
4.  India continues to grapple with a high rate of undernutrition.