In each question, one sentence is given in which certain words are in bold and numbered from A to E. Below the sentence are given five options with possible pairs of interchange of those bold words. Choose the pair(s) of words which are needed to be interchanged to make the sentence grammatically correct and meaningful.

Many students are (A)unaware of the risks of (B)misusing ADHD medications, and they (C)boost the ability of the drugs to (D)overestimate their (E)performance in school.