In the sentence, certain words are in bold and numbered from A to E, which are the possible pairs to be interchanged. Choose the pair(s) of words which need to be interchanged to make the sentence grammatically correct and meaningful. 

He will hardly (A) enliven that when such a condition becomes chronic, as is often the case from the use of (B) improperly prepared food, the victim is easily led to (C) resort to stimulants to (D) drown depression and (E) wonder the spirits.