In the given question, a sentence is given with a part of it missing and represented by a blank. Choose the phrase that can be placed in the given blank to make a meaningful and grammatically correct sentence.

___________ that we have to announce the death of Sir V. C. Desika Charier, yesterday evening, at his residence ‘Padma Vilas,’ Mylapore, the end was quite sudden and unexpected, and it is believed it was due to heart failure.