When you take cells or tissue pieces and grind them with an acid in a mortar and pestle, all the small biomolecules dissolve in the acid. Proteins, polysaccharides and nucleic acids are insoluble in mineral acid and get precipitated. The acid soluble compounds include aminoacids, nucleosides, small sugars etc. When one adds a phosphate group to a nucleoside one gets another acid soluble biomolecule called