Read the following structure which is a combination of:
Clinical Syndrome: Karyotype: Chromosome Formula: Estimated Frequency at Birth
(A). Down Syndrome: 47, +13: 2n + 1 : 1/20,000
(B). Patau Syndrome: 47, +21 : 2n + 1 : 1/2,000
(C). Edward Syndrome: 47, +18 : 2n + 1: 1/8000
(D). Klinfelter Syndrome: 47, XXY : 2n + 1 : 1/500 male births
Choose the correct answer for the above statements from the options given below:
1
(A), (B) and (D) only.
2
(C) and (D) only.
3
(A), (B), (C) and (D).
4
(B), (C) and (D) only.