In addition to histone acetylase complexes, multiprotein chromatin-remodeling complexes are required for activation at many promoters. The first of these complexes characterized was the yeast SWI/SNF chromatin-remodeling complex. One of the SWI/SNF subunits has homology to

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Clamp loader      
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Topoisomerase   
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Helicases     
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OriC

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