PG entrance exam CUET PG 2025 Mock Test Life Sciences Cell Communication and Cell Signaling Immune System
Immunoglobulins have therapeutic applications in cancer treatment, infection clearance and targeted drug delivery. For this reason, immunoglobulins are briefly cleaved by the enzyme pepsin. Following are some of the statements regarding the brief digestion of immunoglobulin by pepsin.
(i) F(ab)2 fragment is generated which retains the antigen binding activity.
(ii) F(ab) fragment having antigen binding activity and the crystallisable Fc fragment are generated.
(iii)The fragment generated on incubation with a proper antigen forms a visible precipitate.
(iv)The fragment generated is incapable of forming a visible precipitate on incubation with a proper antigen.
Which of the above statements are correct?
1
(i) and (ii)
2
(i) and (iii)
3
(i) and (iv)
4
(ii) and (iii)