Actinomycin D inhibits the process of transcription in both prokaryotic and eukaryotic organisms. The following statements are made about actinomycin D- mediated inhibition of transcription:

A. Actinomycin D inhibits transcription from a double stranded DNA template by either E coli or yeast RNA polymerases.

B. Actinomycin D inhibits transcription from a single stranded RNA template by eukaryotic viral RNA polymerases.

C. Actinomycin D inhibits transcription from single stranded ϕx 174 DNA template by ई कोलाई RNA polymerase immediately after viral DNA entry.

D. Actinomycin D inhibits transcription from double stranded RNA template by eukaryotic RNA polymerase II.

Which of the combinations of the above statements is a true representation of the mechanism of actinomycin D mediated inhibition.

1
A only
2
A, B and C
3
A, B and D
4
A and D only

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