A nure is preparing to administer a blood transfusion to a patient with a hemoglobin level of 7 g/dL. Which of the following safety protocols is MOST important to observe during the procedure?

1
Checking the compatibility of the blood with another nurse
2
Warming the blood to body temperature before infusion
3
Infusing the blood slowly over the first 15 minutes and closely monitoring for adverse reactions
4
Pre-medicating the patient with antihistamines to prevent allergic reactions

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