When you take cells or tissue pieces and grind them with an acid in a mortar and pestle, all the small biomolecules dissolve in the acid. Proteins, polysaccharides, and nucleic acids are insoluble in mineral acid and get precipitated. The acid-soluble compounds include amino acids, nucleosides, small sugars, etc. When one adds a phosphate group to a nucleoside, one gets another acid-soluble biomolecule called