In the sentence, certain words are in bold and numbered from A to E, which are the possible pairs to be interchanged. Choose the pair(s) of words which need to be interchanged to make the sentence grammatically correct and meaningful. 

The animals (A) scant a wedge of seawater only 10 meters deep, (B) sealed between the ice above and a (C) barren, rocky seafloor below—a location so remote and (D) hostile that many scientists expected to find nothing but (E) inhabit microbial life.