Which of the followings is a true case definition of confirmed case in Integrated Disease Surveillance Program?

1
It is based on clinical pattern of disease which can be identified by paramedical personal and members of community 
2
It is based on typical history and clinical examination by medical officer of primary and community health centers
3
It is based on clinical diagnosis by a medical officer and positive laboratory identification at primary and community health centers
4
It is based on clinical pattern of disease which can be identified by medical officer of primary and community health centers

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