A male patient with blood type AB, Rh factor positive needs a blood transfusion. The Transfusion Service (blood bank) sends type O, Rh factor negative blood to the unit for the nurse to infuse into this patient. The nurse knows that:

1
This donor blood is incompatible with the patient’s blood.
2
Premedication of the patient with diphenhydramine hydrochloride (Benadryl) and acetaminophen (Tylenol) will prevent any transfusion reactions or side effects.
3
This is a compatible match.
4
The patient is at minimal risk receiving this product since it is the first time he has been transfused with type O, Rh negative blood.

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