Which of the following cytokines are the most important regulators in inflammation and are the targets for anti-inflammatory agents used in rheumatoid arthritis?
1
Tumor necrosis factor-a and Interleukin-1
2
Acetylcholine esterase and Eicosanoids
3
Leukotrienes and Isoprostanes
4
Adhesion factor and Monoamine oxidase A