Identify the wrong statement with reference to the transport of oxygen

1
Higher H+ conc. in alveoli favours the formation of oxyhaemoglobin
2
Low pCO2 in alveoli favours the formation of oxyhaemoglobin
3
Binding of oxygen with haemoglobin is mainly related to partial pressure of O2
4
Partial pressure of CO2 can interfere with O2 binding with haemoglobin

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