In the context of supramolecular chemistry, what is the significance of the "host-guest" relationship?

1
It refers to the covalent bonding between two molecules.
2
It is the interaction where a host molecule forms a complex with a guest molecule through non-covalent interactions, often leading to specific recognition and binding.
3
It describes the process of forming ionic bonds in solution.
4
It pertains to the creation of polymers with high molecular weight

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