In the electron transport chain, the site of proton translocation that is directly driven by the transfer of electrons from ubiquinol (QH2) to cytochrome c by cytochrome c reductase is known to contribute significantly to the proton motive force. This process is critically dependent on the presence of which one of the following components within the inner mitochondrial membrane?

1
Cytochrome c oxidase
2
Cytochrome b6f complex
3
Coenzyme Q and cytochrome c
4
Iron-sulfur (Fe-S) centers

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