A protein coding gene in the mouse was mutated, such that the resultant protein was nonfunctional. The phenotypic effect of the mutation was observed in homozygous mutant mice, in heterozygous mice that inherited the mutation from the mother, and in heterozygous mice, that inherited the mutation from the father.
This suggests that -
1
the gene is imprinted.
2
the mutation acts as a dominant negative.
3
the gene possibly has more than two alleles
4
the gene is X-linked.
5
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