Following statements were made about protein trafficking in cells:

A. Cargo selection occurs when coat proteins bind to the sorting signals either directly or indirectly via adaptor complexes.

B. Protein export from the ER is exclusively mediated through the COPII‐coated vesicles.

C. Identical coat protein is used in the exocytic pathway and/or endocytic pathway.

D. Tethering of the vesicles involves small guanosine triphosphatases (GTPases) of the Rab family.

E. Clathrin‐coated vesicles transport proteins from the plasma membrane to the trans‐Golgi network to late endosomes.

Which one of the following represents the correct combination of above statements?

1
A, B, D
2
A, B, E
3
B, C, D 
4
C, D, E
5
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