The table below lists cell cycle regulatory proteins and their known functions
| Cell Cycle regulatory proteins | Function | ||
| A | Cdk-activating kinase (CAK) | (i) | Suppresses G1/S-Cdk and S-Cdk activation in G1; helps cells withdraw from cell cycle when they terminally differentiate; phosphorylation by Cdk2 triggers its ubiquitylation by SCF. |
| B | Wee1 kinase | (ii) | Suppresses G1/S-Cdk and S-Cdk activities following DNA damage |
| C | p27 (mammals) | (iii) | Phosphorylates inhibitory sites in Cdks: primarily involved in suppressing Cdk1 activity before mitosis |
| D | p21 (mammals) | (iv) | Phosphorylates an activating site in Cdks |
1
A - (iv), B - (iii), C - (i), D - (ii)
2
A- (iii), B - (ii), C - (iv), D - (i)
3
A - (ii), B - (iii), C- (i), D- (iii)
4
A - (i), B- (ii), C - (iii), D - (iv)
5
Question Not Attempted