Teaching Haryana (HPSC) Assistant Professor Mock Test 2025 Life Sciences Cell Communication and Cell Signaling Cellular communication
The extracellular matrix contains a number of non-collagen proteins that typically have multiple domains, each with specific binding sites for other matrix molecules and cell surface receptors. These proteins therefore contribute to both organizing the matrix and helping cells attach to it. The most well characterized matrix protein of this kind is fibronectin. Which one of the following characteristics is NOT TRUE for fibronectin?
1
It is a large glycoprotein found in all vertebrates and important for many cell-matrix interactions.
2
It is composed of three polypeptides that are disulfide bonded into a crosslink structure.
3
In human genome, there is only one fibronectin gene containing about 50 exons, but the transcripts can be spliced in different ways to produce many different fibronectin isoforms.
4
Fibronectin binds to integrin through an RGD motif. Even very short peptide containing RGD sequence can inhibit attachment of cells to fibronectin matrix.
5
Question Not Attempted