Teaching Haryana (HPSC) Assistant Professor Mock Test 2025 Life Sciences Cell Communication and Cell Signaling Cell signaling
Receptor tyrosine kinases (RTKs) form a large and important class of cell surface receptors whose ligands are soluble or membrane bound protein or peptide hormones. Which of the following statement is INCORRECT?
1
All RTKs are transmembrane proteins with extracellular ligand-binding site and a cytosolic domain.
2
Binding of ligand causes most RTKs to dimerize
3
Cytosolic tyrosine kinase phosphorylates a distinct set of tyrosine residues in the cytosolic domain of the dimer.
4
Adapter proteins and enzymes involved in signalling pathways bind to different phosphotyrosine residues via a conserved polypeptide domain called SH2 domain.
5
Question Not Attempted