Given below are protein domains and their binding specificities.

  Column X   Column Y
  Interaction domain    Binding site
A. SH2 domain i. Phosphorylated tyrosine residue on receptors
B. SH3 domain ii. Charged head groups of specific phosphoinositides on plasma membrane
C. PH domain  iii. Short proline-rich amino acid sequence on proteins
D. PTB domain    

Which one of the following options represents all correct matches between Column X and Column Y?

1
A - iii, B - i, C - ii, D - ii
2
A - i, B - ii, C - iii, D - i
3
A - iii, B - iii, C - i, D - ii
4
A - i, B - iii, C - ii, D - i

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