The ratio of total protein content to total RNA content was measured in yeast cells in log phase during growth in minimal media and in minimal media supplemented with amino acid cocktail. In the latter case, the ratio of protein to RNA increased dramatically. Which one of the following is a correct inference from the above information?
1
In minimal medium, proteins are degraded at a higher rate.
2
In amino acid-supplemented culture conditions, fewer ribosomes are simultaneously active on a single transcript.
3
In minimal medium, amino acid availability limits protein translation to a greater extent than transcription.
4
Amino acid supplementation reduces RNA synthesis by modification of RNA Pol II.