Consider the two-way ANOVA model 

Yij = μ + αi + βj + ϵij, i = 1, 2; j = 1, 2

where μ is the overall mean effect, α, is the effect of the i-th level of factor A, βj is the effect of j-th level of factor B, Yij is the response of the (i, j)-th experimental unit and ϵij is the corresponding error with E(ϵij) = 0 for i = 1, 2; j = 1, 2. Which of the following are estimable linear parametric functions?  

1
μ + α2 + β2
2
α1 - β1
3
α2 - β2
4
μ - α1 - β1

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