A DNA sequence is given below:

5' - ATGACGATGACGAGACGATGCAGATGATAGCAGTAGCGAATGAC - 3'

The following primers were designed to amplify the above sequence:

A. 5' - TACTGCT - 3'

B. 5' - CAGTAAG - 3'

C. 5' - ATGACGA - 3'

D. 5' - GTCATTC - 3'

E. 5' - TCGTCAT - 3'

F. 5' - GAATGAC - 3'

If we negate the effects of primer length, Tm, %GC and other factors, which one of the following options represents a combination of primers that could amplify the above DNA sequence?

1
A and C
2
B and D
3
E and F
4
C and D

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