Overexpression of protein 'A' in the brain of Drosophila melanogaster causes the degradation of ovaries in the animal. Overexpression of a secretion-incompetent allele of 'A' does not cause this phenotype. However, downregulation of protein ' B ' in ovaries concomitant with overexpression of protein 'A' in the brain prevents ovary degradation. 'A' and 'B' are found to physically interact in ovary lysates. In the light of the above experiments, which of the following inferences would be correct?
1
The protein 'A' cell autonomously influences ovary development while B is secreted to influence brain function.
2
'A' is a ligand secreted from the brain and 'B' is a receptor in ovaries.
3
'A' is a neurotransmitter secreted from the brain and 'B' is a signal transducer in the ovaries.
4
'A' is a receptor secreted from the ovaries and 'B' is a ligand in the ovary cell membrane.