Match the following components of apoptosis with their respective functions or associated pathways:
| Apoptosis Component | Function / Associated Pathway |
|---|---|
| A) Caspase-3 | 1) Mitochondrial protein involved in cytochrome c release |
| B) Bcl-2 | 2) Anti-apoptotic protein inhibiting mitochondrial outer membrane permeabilization |
| C) Cytochrome c | 3) Activates executioner caspases in the apoptosome |
| D) APAF-1 | 4) Initiator caspase activated by death receptors in the extrinsic pathway |
Select the correct option:
1
A-3, B-1, C-4, D-2
2
A-3, B-2, C-1, D-4
3
A-4, B-3, C-2, D-1
4
A-2, B-1, C-3, D-4