The table below summarizes the key signaling pathways that orchestrate development, their receptors, transcription effectors and output.

  RECEPTOR TRANSCRIPTIONAL EFFECTOR OUTPUT
A Notch CSL/NICD Cell differentiation
B Wnt β-catenin Cell proliferation
C Hedgehog Ci/Gli Developmental growth
D JAK-STAT STAT Immune response regulation
E TGF--β SMAD Cell cycle controOnly A and C

Which of the above pathways is correctly depicted in one of the options given below?

1
Only A and C
2
Only A,B and E
3
Only A and E
4
Only C and E

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