In a series of experiments on zebrafish embryos, the following manipulations were carried out:

Manipulation X: Embryos were treated with a morpholino that knocked down Nodal signaling, which is crucial for mesoderm induction.
Manipulation Y: Embryos were exposed to a chemical agonist of BMP signaling that enhances ventralization.

The following statements were made with respect to the above manipulations and genes involved in body axis formation in zebrafish:

A. The phenotype resulting from manipulation X can be rescued by the injection of Nodal mRNA into the 1-cell stage embryo.

B. Goosecoid mRNA will be more abundant in embryos of manipulation X compared to manipulation Y.

C. Injection of BMP inhibitor into ventral blastomeres induces the formation of a secondary axis.

D. Depletion of Smad5, a downstream effector of BMP signaling, leads to a dorsalized phenotype similar to that obtained from manipulation X.

Which one of the following options represents all correct statements?